Learn about the potential side effects of Topamax (topiramate). Includes common and rare side effects information for consumers and healthcare professionals. Topamax Lawsuits - About. Lawsuits. com. The epilepsy and migraine drug Topamax, which is also available as generic topiramate, has been associated with an increased risk of major birth defects. Research has found higher than expected rates of babies born with cleft lips, cleft palates, genital defects and other birth malformations when the drug is used during pregnancy. TOPAMAX LAWSUIT STATUS: After a string of court losses, the makers of Topamax agreed to settlements for undisclosed amounts in about 7. Topamax birth defect lawsuits.> > SUBMIT INFORMATION ABOUT A TOPAMAX BIRTH DEFECT FOR A LAWYER TO REVIEW A POTENTIAL LAWSUIT< < MANUFACTURER: Topamax is manufactured by Ortho- Mc. Neil Neurologics, a subsidiary of Johnson & Johnson. Generic Topamax versions have been available since 2. We would like to show you a description here but the site won’t allow us. Find out if Topiramate is effective for treating eating disorders and for weight loss with information from the medical experts at Consumer Reports Health. Monotherapy. Topamax, Topamax Sprinkles: 25 mg PO q12hr initially; may increase by 50 mg/day at weekly intervals to 200 mg PO q12hr; Trokendi XR, Qudexy XR: 50 mg PO. What are the possible side effects of topiramate (Topamax, Topamax Sprinkle, Topiragen)? Get emergency medical help if you have any of these signs of an allergic. All of my doctors assure me that the weight loss will slow down eventually, and then I can begin to settle into my new body. I have an irrational fear that they are. OVERVIEW: Topamax (generic topiramate) was first introduced as a medication to treat epilepsy, which is a neurological disorder characterized by recurrent, uncontrolled seizures. In 2. 00. 4, the FDA approved Topamax for an additional use of treating migraines, and it has since become one of the most widely prescribed migraine medications in the United States. The drug is also often prescribed off- label to treat bipolar disorder. TOPAMAX BIRTH DEFECT SIDE EFFECTS: In March 2. FDA issued a warning that Topamax side effects may increase the risk of oral cleft birth defects, such as cleft lip and cleft palate, among babies born to mothers who took the drug during the first trimester of pregnancy. As a result of inadequate warnings previously provided, many women were not aware they may be exposing their baby to a potential risk of Topamax birth defects. The FDA has urged doctors to avoid giving Topamax to pregnant women or women who are of child- bearing age and at a high risk of pregnancy. Alternative epilepsy drugs may not carry the same risk for the unborn child. In July 2. 00. 8, a small study published in the medical journal Neurology identified a potential link between the use of Topamax during pregnancy to an increased risk of serious birth defects. Children born to women who used Topamax during pregnancy were found to develop a cleft lip or palate at a rate 1. The study also indicated that children exposed to Topamax developed genital defects at a rate 1. The FDA required new warnings in 2. North American Antiepileptic Drug Pregnancy Registry found that children born to mothers who took Topamax during the first trimester of pregnancy experienced an oral cleft about 1. TOPAMAX CLEFT LIP AND CLEFT PALATE LAWYERS: Potential lawsuits and class action claims are being reviewed by Topamax lawyers as a result of the drug makers’ failure to adequately research their medication or warn about the potential risk of cleft lip or cleft palate when Topamax is used during pregnancy. Tags: Birth Defect, Cleft Palate and Lip, Epilepsy, Genital Defect, Migraines, Suicide, Topamax. Topamax Dosage, Titration, and Tapering. How to best taper up to therapeutic dosage. Topamax (topiramate) is a medication originally developed for seizure control. It is also FDA approved for Migraine prevention. Dr. Stephen Silberstein, director of the Jefferson Headache Center and Professor of Neurology at Thomas Jefferson University, conducted some of the clinical trials of Topamax for Migraine prevention and prescribes it for some of his patients. He emphasizes that proper dosage and titration (tapering up the dosage) is essential for successful use of Topamax. Here are his recommendations for safely tapering up to a therapeutic dosage level: Week 1: 2. Week 2: 2. 5 mg, twice a day Week 3: 2. Week 4: 5. 0 mg, twice a day Weeks 5 - 7: maintain 5. If that isn't effective in reducing the frequency and severity of Migraine, progress through weeks 8 - 1. Week 8: 5. 0 mg day dose, 7. Week 9: 7. 5 mg, twice a day Week 1. Week 1. 1: 1. 00 mg twice a day Weeks 1. Maintain 1. 00 mg twice a day. If 1. 00 mg twice a day doesn't give the desired results, he recommends tapering down and off Topamax rather than going to a higher dosage because the clinical trials showed no benefit to going higher. Dr. Silberstein also offered some other helpful pieces of information: This medication needs to be taken in a split dose. That means the total daily dosage should be taken in two doses, 1. If you experience the rather common side effect of tingling in your hands and/or feet, ask your doctor about a potassium supplement. This will often stop that side effect. Don't expect a miracle weight loss with Topamax. It is not a primary function of Topamax, but a potential side effect. In the clinical trials, patients who experienced the weight loss side effect lost an average of 3. This is usually a temporary side effect, and the amount of weight lost is proportional to starting body weight. Unless there is an urgent need to discontinue Topamax quickly, it should not be abruptly discontinued. Doing so increases the risk of seizures even in people who have not experienced seizures before. Discontinuing Topamax should be accomplished by reversing the taper used to get to your current dosage under the supervision of your doctor.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. Archives
June 2017
Categories |